EPIDEMIOLOGICAL CHARACTERISTICS AND RELATED RISK FACTORS OF LABOR PRETERM

Abstract

Preterm birth remains a major health problem worldwide, resulting in high neonatal mortality. It is a clinical condition that not only inflicts financial and emotional distress, but can also lead to permanent disability. The present study was conducted to determine risk factors and preventive measures related to preterm birth. This study was observational, retrospective and analytical, which evaluated all pregnant women in a hospital in the city of Guayaquil. Multivariate logistic regression analysis was performed with SPSS version 21. 810 cases were evaluated with a mean age of 28.33 ± 6.1 years (48.7% premature). According to the results of the present study, sexual intercourse during the previous week, multiparity, short intergenic period, preeclampsia, fetal abnormality, rupture of membranes, hypertension and leakage of amniotic fluid, respectively, were risk factors for preterm birth. On the other hand, iron consumption, cephalic presentation, systematic disease, history of caesarean section, prenatal care and mother's weight could be considered protective factors.

Keywords: Preterm birth, risk factor, complications.

References

[1]N. Gomez-Lopez and R. Romero. "Plazyo, Preterm labor in the absence of acute histologic chorioamnionitis is characterized by cellular senescence of the chorioamniotic membranes", Am J Obstet Gynecol. Vol. 217, no. 5, pp. 592.e1–592.e17, 2017.

[2]K. H. Chen, I. C. Chen, Y. C. Yang and  K. T. Chen, "The trends and associated factors of preterm deliveries from 2001 to 2011 in Taiwan", Medicine (Baltimore), Vol. 98, no. 13, pp. e15060, 2019.

[3]J. A. Martin, B. E. Hamilton, M. J. K. Osterman et al, "Births: final data for 2013", Natl Vital Stat Rep, Vol. 64, no. 9, pp. :1–65, 2015.

[4]J. A. Mayo, B. Z. Shachar, D. K. Stevenson et al, "Nulliparous teenagers and preterm birth in California", J Perinat Med, Vol. 45, no.1, pp. 959–67, 2017.

[5]U. Waldenström, S. Cnattingius, L. Vixner and M. Norman, "Advanced maternal age increases the risk of very preterm birth, irrespective of parity: a population-based register study", BJOG, Vol. 124, no. 8, pp.1235-1244, 2017.

[6]M. Delnord, B. Blondel, C. Prunet and J. Zeitlin, "Are risk factors for preterm and early-term live singleton birth the same? A population-based study in France", BMJ Open, Vol. 8, no. 1, pp. e018745, Jan 2018.

[7]A. I Girsen, J. A. Mayo, S. L. Carmichael and C. S. Phibbs, "Women's prepregnancy underweight as a risk factor for preterm birth: a retrospective study", Vol. 123, no. 12, pp. 2001-2007, 2017.

[8]G. M. Shaw, P. H. Wise and J. Mayo, "Maternal prepregnancy body mass index and risk of spontaneous preterm birth", Paediatr Perinat Epidemiol. Vol. 28, no. 4, pp. 302-11, 2014.

[9]D. Drassinower, S. G. Običan, Z. Siddiq et al, "Does the clinical presentation of a prior preterm birth predict risk in a subsequent pregnancy?", Am J Obstet Gynecol Vol. 213, no. 1, pp. 686.e1, 2015.

[10]M. Soltani, "Assessing the risk factors before pregnancy of preterm births in Iran: a population-based case-control study", BMC Pregnancy and Childbirth, Vol. 19, no. 57, pp. 234-9, 2019.