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How to Cite

BorgesM., BorgesM., BorgesJ., & BastidasR. (2020). EXPERIMENTAL STUDY: MANAGEMENT OF METISOPRINOL IN PATIENTS WITH COVID-19. Universidad Ciencia Y Tecnología, 24(103), 41-50. https://doi.org/10.47460/uct.v24i103.356


Covid-19 is a disease characterized by presenting acute respiratory distress syndrome and multi-system dysfunction. The present randomized controlled clinical trial of experimental design was carried out in order to demonstrate the efficacy of metisoprinol in the alternative antiviral management of covid 19, in view of the fact that there is no proven effective treatment in the current global pandemic decreed by the WHO. A population of 60 patients, distributed in groups of 30 (experimental group and a control group) of any age and sex with controlled comorbidities, who presented signs and symptoms of SARS-CoV-2 and S02 greater than 90% breathing air, was evaluated. environment in a clinical phase of less than 15 days attended at home medical consultation in the city of Guayaquil, Ecuador between the period of March and April 2020. This study was developed to determine a pilot protocol that generates fewer adverse effects, avoiding medical complications in symptomatic patients and reverse the clinical and imaging picture. The almost null possibility of persisting signs and symptoms was demonstrated by calculation of relative risk, as well as the presence of lung lesions in imaging controls in 03.33% and 10% rRT-PCR reactivity treated with metisoprinol.

Keywords: COVID-19, SARS-CoV-2, Metisoprinol.


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