Use of the flowers of Cantua buxifolia Juss in the preparation of eye drops for eye irritation
Vol 26 No 114 (2022), Papers
Vol 26 No 114 (2022)

Use of the flowers of Cantua buxifolia Juss in the preparation of eye drops for eye irritation

Papers
https://doi.org/10.47460/uct.v26i114.605
Published June 30, 2022
Enrique Christian Montanchez Mercado
Universidad Nacional Mayor de San Marcos. Lima – Peru.
https://orcid.org/0000-0003-0067-7778
Silvana Yanire Sam Zavala
Universidad Alas Peruanas. Lima–Peru.
https://orcid.org/0000-0001-5676-8914
Pedro Aníbal Solis Cespedes
Universidad Alas Peruanas. Lima, Peru.
https://orcid.org/0000-0002-7339-8721
Maximo Ramirez Julca
Universidad Alas Peruanas. Lima, Peru.
https://orcid.org/0000-0002-1385-3139
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Keywords

toxic dose
ocular irritation
ciprofloxacin
chorioallantoic membrane

How to Cite

Montanchez Mercado, E. C., Sam Zavala, S. Y., Solis Cespedes, P. A., & Ramirez Julca, M. (2022). Use of the flowers of Cantua buxifolia Juss in the preparation of eye drops for eye irritation. Universidad Ciencia Y Tecnología, 26(114), 203-213. https://doi.org/10.47460/uct.v26i114.605
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Abstract

The objective of this work was to compare the different concentrations of eye drops of Cantua buxifolia gus, ex Lam with different substances that allow ophthalmological use without causing acute eye irritation. This method is based on the choroidal asthmatic egg membrane method. (HET-CAM). The results show the weight, volume, density test, and parameters of the egg, as well as fertilization, complying with the criteria specified in HET-CAM Technology - INVITTOX (Protocol 108). Finally, it is concluded that the approach of Cantua buxifolia Juss eye drops, ex Lam, with an irritation index of 1 mg/ml, 2 mg/l, 3 mg/ml is zero and a concentration of 4 mg/ml is the maximum dose tolerated.

Keywords: Toxic dose, ocular irritation, ciprofloxacin, chorioallantoic membrane.

https://doi.org/10.47460/uct.v26i114.605
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References

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